ABSTRACT
133 male patients with type 2 diabetes mellitus were divided into non-atherogenic phenom( N group ) and atherogenic phenom( A group) according to the c utpoint of atherogenic index of plasma (AIP) at 0.06.The clinical chemistry data were compared between two groups.The results showed that body mass index ( BMI ),waist-tohip ratio (WHR),homeostasis model assessment insulin resistance index ( HOMA-IR ) and insulin secretion index (HOMA-IS),serum triglyceride (TG),very low density lipoprotein-cholesterol (VLDL-C),serum uric acid ( SUA ),urine uric acid ( UUA ),and urine micro-albumin ( UMA ) levels in A group were higher than those in N group ( all P＜0.05 ),while high density lipoprotein-cholesterol ( HDL-C ) level was lower ( P＜0.01 ),as well as higher coronary heart disease incidence in A group as compared with N group( P＜0.05 ).Correlation analysis revealed that AIP was positively related with age,BMI,WHR,HOMA-IR,HOMA-IS,systolic blood pressure,diastolic blood poressure,TG,total cholesterol,VLDL-C,SUA,UUA,and UMA( all P＜0.05 ),and negatively related with HDL-C (P＜0.01).Multivariant stepwise linear regression analysis revealed that TG,HDL-C,V LDL-C,and UUA were independent influential factors for AIP.
ABSTRACT
Alc in trial group were significant better than those in control group ( P < 0. 05 ). The results indicate that type 2 diabetic patients with Hp infection should receive moxifloxacin-based triple therapy as first-line treatment.